300 million
people with HBV infection
Hepatitis B virus (HBV) is the world’s most common serious liver infection, with nearly 300 million people living with chronic HBV. Current therapies for HBV aim to suppress the virus but most often do not result in a functional cure.
According to the Hepatitis B Foundation, it is estimated that 1.5 million people become newly infected with HBV each year , and more than 820,000 people die annually from hepatitis B and related complications, including liver cancer.
We are developing RG6346 in collaboration with Roche for the treatment of chronic HBV infection. Unlike current therapies that typically provide long-term suppression of the virus, RG6346 has the potential to contribute to the ultimate goal of providing a functional cure in patients with chronic HBV and is currently being studied in a Phase 2 combination trial conducted by Roche.
References:
- Hepatitis B Foundation. Facts and Figures. Available at: http://www.hepb.org/what-is-hepatitis-b/what-is-hepb/facts-and-figures/. Accessed on June 29, 2021
- Razavi-Shearer D, Gamkrelidze I, Nguyen MH et al. Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study. Lancet Gastroenterol Hepatol. 2018; 3(6):383-403.
- Avert and the World Health Organization. Finding a cure for hepatitis B: are we close? https://www.avert.org/news/finding-cure-hepatitis-b-are-we-close. Accessed Aug. 20, 2021.
Resources for patients with HBV
The following organizations provide educational resources and support research to help people living with HBV.
The Hepatitis B Foundation is dedicated to finding a cure and improving the quality of life for those affected by hepatitis B worldwide. Its work includes funding focused research, promoting disease awareness, supporting immunization and treatment initiatives, and serving as a source of information for patients and their families, the medical and scientific community, and the general public.
The World Hepatitis Alliance (WHA) is dedicated to harnessing the power of people living with viral hepatitis to achieve its elimination. The WHA works with governments, national members and other key partners to raise awareness, influence policy change and drive action to find the millions of people unaware of their condition.
