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Dicerna Pharmaceuticals

Dicerna Pharmaceuticals

Dicerna

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      Directors
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    • Scientific Publications
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    • Nedosiran (formerly DCR-PHXC)
    • RG6346 (formerly DCR-HBVS)
    • DCR-A1AT
    • Collaborative Programs
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  • Patients
    • A Message To Our Patients
    • Patient Advocacy Charter
    • Primary Hyperoxaluria (PH)
    • Hepatitis B Virus
    • Alpha-1 Antitrypsin Deficiency-associated Liver Disease
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Applying RNAi to fight disease

At Dicerna, we use RNA interference, or RNAi, to create medicines that silence or turn off the genes that cause disease. Using our GalXC technology platform, we develop potent and patient-friendly RNAi therapies – in-house and with our partners – for both rare diseases and common diseases with a genetic component.

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GaIXC programs in clinical trials
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GaIXC programs in early-stage development
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Major research and development collaborations

Our GalXC™ pipeline and platform

Our proprietary GalXC technology opens a world of possibilities for creating targeted and potent RNAi therapies. These therapies are thought to be more convenient for patients because they can be delivered under the skin and have a long duration of action.

We currently have three drug candidates in clinical trials:

  • Nedosiran (DCR-PHXC): all three known types of primary hyperoxaluria (PH) 
  • RG6346 (DCR-HBVS): hepatitis B virus (HBV) infection
  • DCR-A1AT: alpha-1 antitrypsin deficiency-associated liver disease

News

Jan

5

2021

Dicerna to Participate in the H.C. Wainwright Virtual BioConnect Conference

Jan

5

2021

Dicerna Announces Novo Nordisk’s Nomination of First Candidate for Development Under RNAi Discovery and Development Agreement and Additional Milestone Achievement

Jan

4

2021

Dicerna Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Events & Presentations

Jan

11

2021

HC Wainwright Bioconnect Conference analyst-led fireside chat

Jan

11

2021

HC Wainwright Bioconnect Conference Scott Gottlieb, M.D. Hosts a Panel on Clinical Trials

Jan

12

2021

Dicerna Corporate Overview

Our commitment to patients

We believe all patients deserve safe and effective medicines that can improve the quality and duration of their lives. Our goal is to understand and ease the unique disease-related burdens of patients and their caregivers as we create new medicines with the potential to restore their health.

Join our team

We’re a company that breaks down the barriers that impede our science or your ambitions. We invite and inspire collaboration among employees, patients, physicians and industry partners throughout the process of drug discovery, development and commercialization.

video preview

Our mission

We interfere with disease

We use RNA interference, or RNAi, to create medicines that silence the genes that cause disease. Our goal is to provide life-changing therapies to people living with rare diseases and common diseases that have a genetic component.

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©2021 Dicerna Pharmaceuticals, Inc. | Lexington, MA
Last revised Apr. 2020

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logo
  • Our
    Company
    • Management Team
    • Board of
      Directors
    • Collaborating
    • Intellectual Property
    • Grants & Charitable Donations
  • Our GalXC™ Technology
    • Scientific Publications
  • Pipeline
    • Nedosiran
      (DCR-PHXC)
    • RG6346 (formerly DCR-HBVS)
    • DCR-A1AT
    • Collaborative Programs
    • Clinical Trials
  • Patients
    • A Message To Our Patients
    • Patient Advocacy Charter
    • Primary Hyperoxaluria (PH)
    • Hepatitis B Virus
    • Alpha-1 Antitrypsin Deficiency-associated Liver Disease
  • Investors & Media
    • Press Releases
    • Events & Presentations
    • Corporate Governance
    • Financials & Filings
    • Stock Information
    • Investor FAQs
    • Contact
  • Careers at Dicerna
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