At Dicerna, we foster a culture of innovation through collaboration.

View our list of career opportunities.


We are dedicated to benefiting patients by advancing science and developing creative solutions to challenging therapeutic problems. Our core values of dedication, innovation, communication, excellence, respect, needs based and accountability drive us personally and as a team, and these are critical factors in the long-term success of our company.

We encourage open dialogue to identify and act upon novel ideas to meet the urgent needs of patients.

As innovators in the emerging area of RNAi, we seek forward-thinking talent to join our growing team, advance our robust pipeline of therapies, and provide ground-breaking medicines to those that depend on us.

Our office location in Cambridge underscores our commitment to being an employer of choice in the Massachusetts life sciences sector, and to being in close proximity to world-class research, academic and healthcare institutions as well as other life sciences leaders. We play an active role in the biotechnology community and in the Alewife business community as the area undergoes a revitalization to become a mini life sciences and technology hub. Our office is close to the MBTA subway and buses, the 120-acre Alewife Reservation, as well as many restaurants and services.


Dicerna is proud to be an Equal Opportunity Employer.

For interest in future employment opportunities, please submit your resume to


Career Opportunities

  • Assoc. Director/Director of Manufacturing

    Posted June 7, 2017



    The Assoc. Director/Director of Manufacturing is responsible for leading and coordinating manufacturing operations at CMOs. The incumbent is responsible for ensuring that current GMP standards, are implemented for the production and the control of Third Party manufactured drug substance and/or drug products.

    Key Responsibilities

    • Manage day to day activities at drug substance and/or drug product contract manufacturing organization (CMOs). Has direct interaction with contract site management (may include being on site at CMO).
    • Proactively manages risks/capability and develops mitigation plans. Identifies and communicates risks and issues that impact quality, compliance, project timelines, resource requirements, finances or the overall business relationship.
    • Review and approve, as required, CMO documentation, including:
      • Analytical, process development and stability protocols, methods and reports
      • Technical review of CMO change documentation
      • Technical review of draft and executed batch records
      • Monitor drug substance and drug product stability programs
      • Write and review CMC sections of regulatory documentation (e.g. pre- IND, scientific advice meetings, IND/IMPD)
    • Participation in audits of current and potential CMOs as technical representative
    • 10% Travel


    • Proven experience in management of GMP manufacturing activities
    • Prior CMC/manufacturing responsibilities in innovator company and the management of Contract Manufacturing Organizations required
    • Oligonucleotide experience highly desirable
    • Demonstrated project management skills and ability to develop effective working relationships with internal/external sites and cross-functional project teams.
    • Experience writing and reviewing CMC sections of INDs/IMPDs
    • BS or MS degree in Chemistry/Chemical Engineering + 8-10 years of related experience in the biotechnology/pharmaceutical industry.

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