DELIVERING RNAi-BASED BREAKTHROUGH THERAPIES

To Improve Lives

Our Pipeline

Dicerna is developing innovative RNAi therapies for the treatment of rare diseases involving the liver and genetically defined cancer targets.

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Unlocking the Potential of RNAi

RNA interference (RNAi) is a natural biological method for silencing or “turning off” specific genes known to cause or drive disease. In the RNAi process, small, carefully selected molecules of RNA inhibit the expression of these harmful genes by causing the targeted destruction of their messenger RNAs (mRNA). RNAi has the potential to generate a revolution in medicine.

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Dicerna’s RNAi Mechanism of Action

Unlocking the potential of RNAi

RNAi: Timeline of Technological and Therapeutic Advances